Please note that we will be using QuPath version 0.3.2. For this post, we’ll be focusing on the MIRAX format, but the general steps can be generalized to other image formats openable in QuPath. These tiles can be useful for training machine learning classifiers or in general for working with your images in other programs that are not well suited for whole slide image formats. Here we’ll show you step-by-step how to use QuPath annotations and scripting to export smaller, full-resolution tiles of large whole slide histology images. vms) are often massive when uncompressed (>40 GB) and are commonly used when imaging tissue sections for histology. With slide scanners and other automated, high-throughput microscopes becoming more and more common, it’s important to understand how to work with the large image files they produce.