As a potential security risk, Sherry's safety was important to her parents, who wanted her to stay away from strangers who could be after Golgotha. Her mother also entrusted her with a locket, disguised as her 11th birthday present, that was related to her and William's research. Little else is known of this stage of Sherry's life, although she was enrolled as a student at East Raccoon Elementary. Her parents were senior researchers of the G-Virus Project, a eugenics project that oversaw the creation of Golgotha, a Progenitor strain they believed could be used to improve the human race. Sherry's relationship with her parents was strained due to their busy work schedules and, despite their early 1990s transfer to NEST in the industrial district, she was frequently neglected.
Sherry was born around the year 1986 to Doctors William and Annette Birkin, two virologists who took part in t-Virus research at Umbrella's isolated Arklay Laboratory.